Joint Supplement Comparison for Horses Dose Amount Loading Dose Approved for Pets Hyaluronic Acid (HA) Methyl Sulfonyl Methane (MSM) Glucosamine Hydrochloride Glucosamine Sulfate Chondroitin Sulfate Yucca Grape Seed Extract Other Ingredients LubriSyn HA Joint Supplement for Horses and Pets 1/2 oz 1 oz daily for 3-4 days Yes 75 mg per 1/2 oz LubriSyn HA+ Horse and Pet Joint Supplement 1/2 oz 1 oz daily for 10 days Yes 75 mg per 1/2 oz 150 mg per 1/2 oz Majesty's Flex Wafers Joint Supplement for Horses 1 wafer 1-2 wafers daily for 1 month No 2,500 mg per wafer 2,500 mg per wafer 600 mg per wafer 1,250 mg per wafer 500 mg ascorbic acid Majesty's Flex HA Wafers Joint Supplement for Performance Horses 1-2 wafers No 150 mg per wafer 2,500 mg per wafer 2,500 mg per wafer 600 mg per wafer 2,500 mg per wafer 1,000 mg vitamin C Majesty's Flex XT Wafers Increased Joint Support Supplement for Horses 1-2 wafers No 3,000 mg per wafer 7,500 mg per wafer 600 mg per wafer 1,750 mg per wafer 750 mg ascorbic acid MaxFlex XR Joint Formula 1/2 oz No 10 mg per 1/2 oz 100 mg per 1/2 oz 5,000 mg per 1/2 oz 50 mg per 1/2 oz 50 mg Ester-C and 10 mg manganese sulfate Mega Grand Flex Joint Supplement for Horses and Dogs 1 oz Yes 10,000 mg per 1 oz 2,500 mg per 1 oz 100 mg per 1 oz 1,000 mg vitamin C, 1,000 mg methionine, 250 mg manganese gluconate, 200 mg zinc gluconate, 200 mg lysine, 150 mg niacinamide, 100 mg bioflavonoids, 80 mg proline and 50 mg copper gluconate Mega-MSM Horse Joint Supplement 20 gm 40 gm for 1 week No 10,000 mg per 20 gm Missing Link Well Blend + Joint for Horses 1/3 cup No min 4,800 mg/ max 5,200 mg per 1/3 cup min 2,000 mg linoleic acid (omega-6), min 5,200 mg alpha-linolenic acid (omega-3), MSM EQ Joint Supplement 10 gm 20 gm for 1 week Yes 10,000 mg per 10 gm MSM Horse Supplement 1 oz No 99.9% pure MSM MSM Joint Supplement for Horses 10 gm 20 gm for 1 week No 10,000 mg per 10 gm MSM Pure Powder 1 Tbsp 1 Tbsp twice daily for 6 days Yes 100% ultra pure MSM MSM Pure Horse Supplement 1/4 oz 1/3 oz daily No 99.7% pure MSM Disclaimer: The information shown here has been gathered from many sources and with great care. Recognizing, however, the possibility of human and typographical errors in transposing such a large amount of technical information, PBS Animal Health hereby disclaims responsibility. Updated 7/20/22